Paul Zamecnik

Scientist, Award Winner

1912 – 2009

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Who was Paul Zamecnik?

Paul Charles Zamecnik was an American scientist who played a central role in the early history of molecular biology. He was a professor of medicine at Harvard Medical School and a senior scientist at Massachusetts General Hospital. Zamecnik pioneered the in vitro synthesis of proteins and helped elucidate the way cells generate proteins. With Mahlon Hoagland he co-discovered transfer RNA. Through his later work, he is credited as the inventor of antisense therapeutics. Throughout his career, Zamecnik earned over a dozen US patents for his therapeutic techniques. Up until his death in 2009 he maintained a lab at MGH where he studied the application of synthetic oligonucleotides for chemotherapeutic treatment of drug resistant and XDR tuberculosis in his later years.

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Born
1912
Cleveland
Also known as
  • Paul C Zamecnik
Nationality
  • United States of America
Profession
Education
  • Dartmouth College
  • Harvard Medical School
Lived in
  • Cleveland
Died
Oct 27, 2009

Submitted
on July 23, 2013

Citation

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