William Theilheimer

Who was William Theilheimer?

William Theilheimer, who was born in Augsburg, Germany, played a significant role in the history of what is now known as chemoinformatics.

He received his Ph.D in organic chemistry from Basel University, Switzerland in 1940. Being Jewish, Basel provided a safe haven for him during the Second World War and he stayed there until 1947 as Assistant to Professor Hans Friedrich Albrecht Erlenmeyer, the son of Friedrich Gustav Carl Emil Erlenmeyer and grandson of Richard August Carl Emil Erlenmeyer. During his time there he compiled the data for the first two volumes of "Synthetische Methoden der Organische Chemie" published by S. Karger Verlag in Basel in 1946 and 1948. These built on the system of Conrad Weygand for grouping similar reactions together, but used "Theilheimer reaction symbols" that summarised the most significant bond formed, the reaction type, and the bond broken or fragment lost, as well as a specific reagent order based on the periodic table.