John W. Huffman

Who is John W. Huffman?

John William Huffman is a professor emeritus of organic chemistry at Clemson University who first synthesised many novel cannabinoids. His research, funded by the National Institute on Drug Abuse, was focused on making a drug to target endocannabinoid receptors in the body.

Beginning in 1984, Huffman and his team of researchers began developing cannabinoid compounds to aid in research of multiple sclerosis, HIV/AIDS, and chemotherapy. Over the course of twenty years, Huffman and his team developed 450 synthetic cannabinoid compounds which were used to test the effect of cannabinoid receptors in the brain and other organs. Ultimately, the cannabinoid research provided understanding of diseases and information for medication development. In the late 2000s, two of Huffman's cannabinoid compounds began being sold in Germany as marijuana alternatives known as K2 and Spice. "I figured once it got started in Germany it was going to spread. I'm concerned that it could hurt people," Huffman said. "I think this was something that was more or less inevitable. It bothers me that people are so stupid as to use this stuff".