Adolphe-Marie Gubler

Who was Adolphe-Marie Gubler?

Adolphe-Marie Gubler was a French physician and pharmacologist born in Metz.

Originally a student of botany, he began his medical studies in 1841 at Paris, where he was a pupil of Armand Trousseau. In 1845 he became an interne des hôpitaux, earning his doctorate in 1849. Afterwards he worked as a physician at the Hôpital Beaujon, and in 1853 earned his agrégation with a thesis on cirrhosis of the liver. In 1868 he was appointed professor of therapy to the medical faculty in Paris, maintaining this position until his death in 1879.

Gubler made a number of contributions in the fields of medicine and pharmacology. He is credited with being the first physician to differentiate between hemotogenous and hepatogenous icterus. His name is associated with "Millard-Gubler syndrome", a condition characterized by softening of brain tissue that is caused by blockage of blood vessels of the pons. The disease is named in conjunction with Auguste Louis Jules Millard, who initially described the disorder in 1855. The eponymous "Gubler's line" is a line of superficial origin of the trigeminal nerve on the pons, a lesion below which results in the aforementioned Millard-Gubler syndrome.