Edward Tobinick

Who is Edward Tobinick?

Edward Lewis Tobinick is an American physician who is the inventor of new methods of treatment of neurological disorders. Dr. Tobinick is co-author of the recent case report documenting rapid clinical improvement in a patient with Alzheimer's disease following perispinal administration of etanercept which has been received with considerable interest. Wyeth in collaboration with the University of Southampton has, as of January 2011, begun enrollment into a randomized, placebo-controlled clinical trial of etanercept for patients with Alzheimer's disease. Also being trialed currently, in a multi-center study, is the use of epidural etanercept for sciatica, for which favorable randomized, placebo-controlled clinical data from Walter Reed Army Medical Center were published in 2009. Etanercept is a potent inhibitor of a cytokine called TNF.

Tobinick is also lead author of a December 2012 study that provided evidence that excess TNF contributes to chronic neurological, neuropsychiatric and clinical impairment after stroke and Traumatic brain injury and that perispinal etanercept was therapeutically useful for these indications.