Harold Frost

Surgeon, Deceased Person

1921 – 2004


Who was Harold Frost?

Harold M. Frost was an US-American orthopedist and surgeon considered to be one of the most important researchers and theorists in the field of bone biology and bone medicine of his time. He published nearly 500 peer-reviewed scientific and clinical articles and 16 Books and is according to the Science Citation Index one of the most cited investigators in skeletal research.

His main academic inputs included:

Development of Bone Histomorphometry for description of cellular based bone formation and Bone resorption processes

the eleventh rip Biopsy used for diagnosis of metabolic Bone diseases

Research on the multi-cellular unit as a key to bone metabolism

the experimental proof that Estrogen reduces bone formation

the histological proof of micro-damages in human bone biopsies

the basic model of the adaptation of the Growth plate to mechanical stress

the Utah-Paradigm of Bone physiology, an enhancement of Wolff's law stating that Bone adapts to mechanical stress and that hence there is a close link between muscle and bone

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  • United States of America
Jun 19, 2004

on July 23, 2013


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