Harold Frost
Surgeon, Deceased Person
1921 – 2004
Who was Harold Frost?
Harold M. Frost was an US-American orthopedist and surgeon considered to be one of the most important researchers and theorists in the field of bone biology and bone medicine of his time. He published nearly 500 peer-reviewed scientific and clinical articles and 16 Books and is according to the Science Citation Index one of the most cited investigators in skeletal research.
His main academic inputs included:
Development of Bone Histomorphometry for description of cellular based bone formation and Bone resorption processes
the eleventh rip Biopsy used for diagnosis of metabolic Bone diseases
Research on the multi-cellular unit as a key to bone metabolism
the experimental proof that Estrogen reduces bone formation
the histological proof of micro-damages in human bone biopsies
the basic model of the adaptation of the Growth plate to mechanical stress
the Utah-Paradigm of Bone physiology, an enhancement of Wolff's law stating that Bone adapts to mechanical stress and that hence there is a close link between muscle and bone
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