Harvey J. Alter

Who is Harvey J. Alter?

Harvey James Alter is an American medical researcher, virologist, and physician who is best known for his work that led to the discovery of the hepatitis C virus. Alter is the chief of the infectious disease section and the associate director for research of the Department of Transfusion Medicine at the Warren Grant Magnuson Clinical Center in the National Institutes of Health. In the mid-1970s, Alter and his research team demonstrated that most post-transfusion hepatitis cases were not due to hepatitis A and hepatitis B viruses. Working independently, Alter and Edward Tabor, a scientist at the U.S. Food and Drug Administration, proved through transmission studies in chimpanzees that a new form of hepatitis, initially called “non-A, non-B hepatitis” caused the infections, and that the causative agent was probably a virus. This work eventually led to the discovery of the hepatitis C virus in 1988.

Alter has received recognition for the research leading to the discovery of the virus that causes hepatitis C.