Susan Marqusee

Who is Susan Marqusee?

Susan Marqusee is professor of molecular and cellular biology at UC Berkeley and Berkeley director of the California Institute for Quantitative Biosciences (QB3). Her research focus is on protein engineering, with the long-term goal of understanding the structural and dynamic information encoded in the linear sequence of amino acids. She and her colleagues have developed several methodologies, including the application of novel hydrogen exchange techniques and the mechanical manipulation of single protein molecules, to probe the energy landscape — cellular dynamics and function — of proteins, including proteins from thermophilic organisms that retain their native structures under extreme conditions. Other projects in her lab focus on the mechanism of protein misfolding, the structural and energetic mechanism of signaling, computational identification of folding modules, and the role of ligand binding. She holds an M.D and a Ph.D. from Stanford University and has been on the UC Berkeley faculty since 1992.